SARS-COVID-19 antibodies in pregnant women at a level III hospital in Peru / SARS-COVID-19 antibodies in pregnant women at a level III hospital in Peru / Anticuerpos anti-SARS-COV-2 en gestantes en un hospital nivel III de Perú

RESUMEN Introducción . La enfermedad de COVID-19 se propaga rápidamente. Se desconoce la seroprevalencia en mujeres embarazadas que ingresan a hospitalización y sus características propias en este tipo de población en Perú. Objetivo . Determinar la prevalencia y características clínico-epidemiológicas de gestantes con anticuerpos anti-SARS-CoV-2 en un hospital nivel III de Perú. Métodos . Estudio observacional de tipo transversal, realizado en el Instituto Nacional Materno Perinatal de Perú, entre el 15 de abril y 15 de mayo de 2020. Participaron todas las gestantes que ingresaron a hospitalización y fueron tamizadas para la infección por SARS-CoV-2 mediante pruebas serológicas, cuyos resultados fueron analizados conjuntamente con sus características clínicas y epidemiológicas, utilizando estadígrafos descriptivos e intervalos de confianza al 95%, y mediante la prueba de independencia de chi cuadrado con una significancia de 0,05. Resultados . Se tamizaron 2 419 embarazadas, identificando una prevalencia de 7,0% con resultados positivos a los anticuerpos anti-SARS-CoV-2 (IC95%: 6,1% a 8,1%). Se observó IgM en 10% (IC95%: 6,1% a 15,8%), IgM/IgG en 78,8% (IC95%: 71,8% a 84,6%), IgG en 11,2% (IC95%: 7% a 17,1%). El 89,4% de gestantes seropositivas fueron asintomáticas. Se observó como complicaciones obstétricas más frecuentes la rotura prematura de membranas (11,8%) y la preeclampsia (6,5%). No se halló asociación de las características clínico epidemiológicas y el tipo de respuesta serológica para el virus SARS-CoV-2 (p>0,05). Conclusiones . Las gestantes con ingreso hospitalario en el periodo estudiado presentaron prevalencia de anticuerpos anti-SARS-CoV-2 de 7,0%, siendo mayormente asintomáticas. No se evidenció asociación entre las características clínico-epidemiológicas analizadas y el tipo de respuesta de los anticuerpos anti- SARS-CoV-2.

ABSTRACT Introduction: COVID-19 disease spreads rapidly. Seroprevalence in pregnant women entering for hospitalization and clinical characteristics in this type of population in Peru is not known. Objective: To determine the prevalence and clinical-epidemiological characteristics of pregnant women with anti-SARS-CoV-2 antibodies at a level III hospital in Peru. Methods: Observational and cross-sectional study performed at the National Maternal Perinatal Institute of Peru. Pregnant women admitted for hospitalization were screened for COVID-19 infection. Results of anti-SARSCoV-2 serological tests and information on maternal and perinatal characteristics were obtained. Data analysis was performed using descriptive statistics and 95% confidence intervals. Results: In 2 419 pregnant women screened we identified a prevalence of 7.0% of anti-SARS-CoV-2 antibodies (95% IC: 6.1% to 8.1%), including IgM in 10% (95% IC: 6.1% to 15.8%), IgM / IgG in 78.8% (95% IC: 71.8% to 84.6%), IgG in 11.2% (95% IC: 7.0% to 17.1%). 89.4% of the seropositive pregnant women were asymptomatic. Most frequent complications were premature rupture of membranes (11.8%) and preeclampsia (6.5%). No association was found between clinical and epidemiologic characteristics and type of serological response to SARS-CoV-2 (p > 0.05). Conclusions: Pregnant women had prevalence of anti-SARS-CoV-2 antibodies of 7.0% on admission to the hospital; most of them were asymptomatic. There was no association between clinical-epidemiological characteristics analyzed and type of anti-SARS-CoV-2 antibody response.

Investigating supply chain research trends amid Covid-19: a bibliometric analysis: MRN

PurposeThe purpose of this study is to analyse the effects of Covid-19 on the supply chain management and to provide an agenda for future research in this context.Design/methodology/approachBy using the SCOPUS database, a total of 191 articles of 1,323 research articles were selected for further analysis. Bibliometric analysis and science mapping were performed which included author influence, affiliation statistics, keywords, citations, co-citation and co-word analysis.FindingsFive clusters were identified in the context of supply chain management under Covid-19: managing disruptions in global food supply chains (SCs), using Industry 4.0 technologies for sustainable SCs, collaboration across the supply network for contingency situations, coping with disease outbreaks in personal and professional lives and countering the ripple effect of pandemics. These clusters are potential areas for future research.Originality/valueLiterature is still rare about SC practices amid the Covid-19 crisis. Therefore, this study attempts to provide insights and fill the current gaps on this field.

Resonance Triggers and the Formation of Pandemic Coronavirus Discourse

The article examines the mechanism of the formation of a resonant discourse using the example of a discourse about the pandemic coronavirus. Special attention is paid to the concept of "trigger” and the characteristics of the main triggers of the coronavirus pandemic discourse. The article describes the communicative and cognitive potential of the triggers "Fear” and "Isolation”. They are manifested in lexical and semantic innovations, in the word-formation activity of the language, in the expansion of associative links. A trigger is viewed as a semantic mechanism that defines strategies for generating text and the formation of a communicative event based on a real event, which caused a public outcry. Concentration of linguistic resources on the event contributes to the formation of a new discursive formation, thematically related to a resonant event generating new structures of sociocultural knowledge. © Siberian Branch of the Russian Academy of Sciences, Institute of Philology. All rights reserved.

Fighting Pandemic: The Mobile Application Way (a Case of the Aarogya Setu App)

The world of the COVID-19 pandemic is an anomalous biosphere with nothing to be forecasted. The main concern of every individual is focused on keeping themselves safe from infection. This need of keeping oneself safe has raised an alarming situation and resulted into quasi self-quarantines and self-imposed seclusion. The pandemic has increasingly put pressure on the healthcare system of different countries, wherein the countries with the limited number of doctors and health staff are finding it increasingly difficult for all intent and purposes to treat the patients. To lay off the load of medical staff all around the world, different countries have adopted their own unique technique of handling the calamity. One of the creations is applications on smartphones. This has resulted in increasing awareness, self-detection of coronavirus symptoms among the population. These applications were designed to increase awareness among individuals of any risk in their surroundings. It has been developed by corporates, governments and NGOs. The Indian government also launched its own indigenous app named Aarogya Setu (Bridge of Health) to capacitate people to handle and self-detect coronavirus symptoms. The present case is an effort to understand the adoption of Aarogya Setu app from the eye of diffusion of innovation. Case Objective Objectives of the case are to make readers aware about the coronavirus-related applications launched during pandemic, criteria for diffusion of innovation and the concepts of adoption.

The Coronavirus Shopping Anxiety Scale: initial validation and development

PurposeThe purpose of this study is to develop a scale to measure coronavirus shopping anxiety. Numerous studies have developed a scale for measuring coronavirus anxiety and fear, notably absent is a concerted effort to review and assess the impact of coronavirus on the shopping anxiety of consumers. This scale fulfills this gap.Design/methodology/approachThe steps taken for checking the various psychometrics of the scale include item generation, followed by exploratory factor analysis (EFA) through SPSS and confirmatory factor analysis through AMOS. The data were collected from over 208 respondents.FindingsThis study resulted in the development of a nine-item scale with robust psychometric properties. The scale resulted in highlighting two factors related to anxiety: in-store shopping anxiety and online shopping anxiety.Research limitations/implicationsThe scale developed has the desirable reliable and valid properties that could be used by aspiring researchers.Practical implicationsThe scale developed highlighted that the restrictions in shopping impact the mental health and psychology of consumers. The scale resulted in analyzing the factors related to shopping anxiety, which could give top management a perspective and vision to look into the minds of the consumer's shopping anxiety behaviors.Social implicationsCompanies, firms, health professionals and marketers could use this scale to investigate the various shopping anxiety perceptions among consumers in society.Originality/valueThis research fills the gap by developing a first nine-item scale based on the qualitative research and quantitative assessment for measuring shopping anxiety caused due to the pandemic.

Features of Medical Care Providing to Patients with Digestive Diseases in the Krasnodar Region during the COVID-19 Pandemic

The aim of the study: optimization the medical care provision to patients with diseases of the digestive system (DD) in the Krasnodar Region during the COVID-19 pandemic. Material and methods. The analysis of the features of the DD course in the Krasnodar Region was carried out according to the data of form C 51 "Distribution of the dead by sex, age groups and causes of death” of the Territorial Federal State Statistics Service in the Krasnodar Region, as well as monitoring the quality of medical care for patients with DD for the period from 2019 to 2021 years. Results. During the COVID-19 pandemic, the routing of gastroenterological patients, dispensary observation and preventive measures have undergone some changes. In the structure of total mortality in the Krasnodar Region, mortality from DD was 21.6 % in 2020 and 4.0 % in 2021. The decrease in the growth of mortality rate, including from DD, in the second year of the pandemic is associated with the completed healthcare systems reformatting. The increase in hospital mortality in patients with gastric and duodenal ulcers, ulcerative colitis, and diverticular disease had a significant impact on mortality rates from DD. The decreasing number of hospitalizations was explained due to the conversion of a number of hospitals into hospitals for the treatment of patients with COVID-19. The hospitalization was mainly carried out for emergency indications and patients with a more severe course of the disease. The pandemic has increased the need for telemedicine: 378 tele-consultations on the gastroenterological profile was carried out in the Krasnodar Region in 2021. Conclusion. Healthcare system workload in the Krasnodar Region increased significantly during the coronavirus pandemic that required a number of structural adjustments. In recent times, the regional health care is returning to the planned mode of providing medical care. © 2022 Russian Journal of Gastroenterology, Hepatology, Coloproctology

Maintaining places of social inclusion: Ebola and the emergency department

We introduce the concept of places of social inclusion-institutions endowed by a society or a community with material resources, meaning, and values at geographic sites where citizens can access services for specific needs-as taken-for-granted, essential, and inherently precarious. Based on our study of an emergency department that was disrupted by the threat of the Ebola virus in 2014, we develop a process model to explain how a place of social inclusion can be maintained by custodians. We show how these custodians-in our fieldsite, doctors and nurses-experience and engage in institutional work to manage different levels of tension between the value of inclusion and the reality of finite resources, as well as tension between inclusion and the desire for safety. We also demonstrate how the interplay of custodians' emotions is integral to maintaining the place of social inclusion. The primary contribution of our study is to shine light on places of social inclusion as important institutions in democratic society. We also reveal the theoretical and practical importance of places as institutions, deepen understanding of custodians and custodianship as a form of institutional work, and offer new insight into the dynamic processes that connect emotions and institutional work. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

Influences of Coronavirus on Societies

Coronavirus disease 2019 is a tiny self-replicated agent that is peculiarly found in humans and animals. A total of seven human Coronavirus types have been well-known to cause infectious disease in humans. They are known to infect the neurological and respiratory systems mostly. The first human Coronavirus identified in mid-1960's and then have seen widespread outbreaks in the form of Middle East respiratory syndrome Coronavirus (MERS-CoV) and severe acute respiratory syndrome related Coronavirus (SARS-CoV). However, we see the emergence of another outbreak due to a new virus called the SARS-CoV-2 virus. This COVID-19 novel disease infected people first time in Wuhan, China. As the number of infected cases rises, it is clear that these pandemics pose a threatening impact on social and economic sectors. The general overview of Coronavirus will be explained in this article and also enlightened some of significant social and economic factors influenced by the novel COVID-19.

SARS-CoV-2, the pandemic coronavirus: Molecular and structural insights.

The outbreak of a novel coronavirus associated with acute respiratory disease, called COVID-19, marked the introduction of the third spillover of an animal coronavirus (CoV) to humans in the last two decades. The genome analysis with various bioinformatics tools revealed that the causative pathogen (SARS-CoV-2) belongs to the subgenus Sarbecovirus of the genus Betacoronavirus, with highly similar genome as bat coronavirus and receptor-binding domain (RBD) of spike glycoprotein as Malayan pangolin coronavirus. Based on its genetic proximity, SARS-CoV-2 is likely to have originated from bat-derived CoV and transmitted to humans via an unknown intermediate mammalian host, probably Malayan pangolin. Further, spike protein S1/S2 cleavage site of SARS-CoV-2 has acquired polybasic furin cleavage site which is absent in bat and pangolin suggesting natural selection either in an animal host before zoonotic transfer or in humans following zoonotic transfer. In the current review, we recapitulate a preliminary opinion about the disease, origin and life cycle of SARS-CoV-2, roles of virus proteins in pathogenesis, commonalities, and differences between different corona viruses. Moreover, the crystal structures of SARS-CoV-2 proteins with unique characteristics differentiating it from other CoVs are discussed. Our review also provides comprehensive information on the molecular aspects of SARS-CoV-2 including secondary structures in the genome and protein-protein interactions which can be useful to understand the aggressive spread of the SARS-CoV-2. The mutations and the haplotypes reported in the SARS-CoV-2 genome are summarized to understand the virus evolution.

Substantial reduction of healthcare facility-onset Clostridioides difficile infection (HO-CDI) rates after conversion of a hospital for exclusive treatment of COVID-19 patients.

Healthcare facility-onset Clostridioides difficile infection rates substantially dropped in a Mexican hospital after its conversion to a full COVID-19 setting, despite heavy contamination of the environment the previous year. Better adherence to hand hygiene and contact precautions may help explain this finding.

Respiratory and ventilator management of COVID-19.

The current pandemic of COVID-19 has infected around 2.5 million people with more than 125,000 deaths across the globe till date, and numbers are still rising. The causative organism is a virus of corona family. The International Committee on Taxonomy of Viruses (ICTV) named it severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) due to its similarities with the virus was caused SARS outbreak (SARS-CoV). Although most of the patients present with less severe symptoms like rhinitis, cough, fever, and mild flu-like symptoms, it may progress to severe acute respiratory illness, pneumonia or acute respiratory distress syndrome (ARDS) mainly in immunocompromised hosts. Severe infections mainly involve lungs, and compromise its capacity of ventilation. Respiratory and mechanical ventilation is one of the important parts of management.